Carnosine is a naturally occurring substance in the body that serves as a primary building component of the cell and is also capable of regenerating it. At the same time, it ensures communication between cells, thereby enabling the automatic functioning of our organism.
Research is carried out by experts in many countries around the world, including MUDr. Michael Kučera. A Czech internal medicine physician, he has been cooperating since 1994 with Prof. Dr. R. M. Baevsky (Institute of Biomedical Problems of the Russian Academy of Sciences) in the field of applying space medicine in practice, primarily in the area of prevention and strengthening of adaptive mechanisms to stress. The research activities of the internationally recognized expert in mitochondrial medicine, Dr. Kučera, were awarded the IMMA-Prize 2000 in the year 2000 for clinically relevant achievements in this field.
In recent years, increasing attention and interest have been devoted to the phenomenon of carnosine properties, which is considered a substance of the century and is assumed to become a fundamental daily remedy for people of all ages, especially those who have reached the age of 40 and older. Research projects concerning carnosine are being carried out in the USA, Australia, Great Britain, Japan, Scandinavia, Russia, and China, and it is recommended by specialists dealing with aging as an important and valuable dietary supplement. Carnosine is being studied by many top scientific researchers, e.g. Dr. Bruce Ames and his team from UCLA Berkeley (University of California, Los Angeles). No one doubts his high level of expertise in molecular biology.
Laboratory research in the field of cellular senescence (aging) – i.e. the end of the life cycle of two dividing cells – demonstrates that the obtained facts cannot be merely coincidental. Carnosine has remarkable abilities to rejuvenate cells undergoing senescence, restore their normal properties, and extend their lifespan. How can carnosine rejuvenate cells? So far, not all answers are known, but the properties of carnosine point to key mechanisms of cellular and tissue aging – it protects against telomere shortening and against DNA damage during cell division.
Furthermore, a range of beneficial effects on the organism has been demonstrated. The mechanisms of these effects are characterized by the following processes: Physiological (normal concentrations (20–30 μM/l) in standard in vitro media prolong the lifespan of human fibroblasts and strongly reduce their manifestations of aging.
Carnosine could therefore be very useful in the following age-related conditions:
neurological degenerative diseases (Alzheimer’s and Parkinson’s disease, epilepsy, depressive disorders, schizophrenia, mild cognitive impairment, dementia of various etiologies, conditions after cerebrovascular accidents),
autism spectrum disorders (Asperger’s syndrome, ADHD, dyslexia and dyspraxia, Tourette’s syndrome, etc.),
general disorders of cellular aging,
cross-linking of the eye lens, cataract,
cross-linking of skin collagen (skin aging),
formation of AGEs (= Advanced Glycation End Products), i.e. advanced end products of protein glycation,
conditions of accumulation of damaged proteins,
muscular dystrophies,
cardiovascular diseases,
cerebrovascular disorders,
diabetes and its complications.
It is a physiological and 100% natural super-antioxidant with a spectrum of biological functions (in addition to the properties mentioned above):
has universal and multifaceted antioxidant activity,
supports muscle vitality,
increases muscle strength and endurance,
accelerates recovery after sprints,
reduces cellular damage caused by alcohol,
acts as a transmitter of impulses in the brain and nerves.
